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Questions about Carrageenan?

WALDO, Maine (Ingredient Solutions) — Last month, activist group The Cornucopia Institute formally requested that the FDA remove common food additive carrgeenan from the food supply, arguing that the additive was unsafe for human consumption.

Ingredient Solutions, Inc. has released the following information in response to consumer concern over the food additive carrageenan.

Q: What is carrageenan?

A: Carrageenan is a naturally-occurring seaweed extract. It is widely used in foods and non-foods to improve texture and stability. Common uses include meat and poultry, dairy products, canned pet food, cosmetics and toothpaste.

Q: Why the controversy?

A: Self-appointed consumer watchdogs have produced numerous web pages filled with words condemning carrageenan as an unsafe food additive for human consumption. However, in the more than 70 years of carrageenan being used in processed foods, not a single substantiated claim of an acute or chronic disease has been reported as arising from carrageenan consumption. On a more science-based footing, food regulatory agencies in the U.S., the EU, and in the UN’s Food and Agriculture Organization/World Health Organization (FAO/WHO) repeatedly review and continue to approve carrageenan as a safe food additive. 

Q: What has led up to this misrepresentation of the safety of an important food stabilizer, gelling agent and thickener?

A: It clearly has to be attributed to the research of Dr. Joanne Tobacman, an Associate Professor at the University of Illinois in Chicago. She and a group of molecular biologists have accused carrageenan of being a potential inflammatory agent as a conclusion from laboratory experiments with cells of the digestive tract. It requires a lot of unproven assumptions to even suggest that consumption of carrageenan in the human diet causes inflammatory diseases of the digestive tract. The objectivity of the Chicago research is also flawed by the fact that Dr. Tobacman has tried to have carrageenan declared an unsafe food additive on weak technical arguments that she broadcast widely a decade before the University of Chicago research began.

Q: What brings poligeenan into a discussion of carrageenan?

A: Poligeenan (“degraded carrageenan” in pre-1988 scientific and regulatory publications) is a possible carcinogen to humans; carrageenan is not. The only relationship between carrageenan and poligeenan is that the former is the starting material to make the latter. Poligeenan is not a component of carrageenan and cannot be produced in the digestive tract from carrageenan-containing foods.

Q: What are the differences between poligeenan and carrageenan?

A: The production process for poligeenan requires treating carrageenan with strong acid at high temp (about that of boiling water) for six hours or more. These severe processing conditions convert the long chains of carrageenan to much shorter ones: ten to one hundred times shorter. In scientific terms the molecular weight of poligeenan is 10,000 to 20,000, whereas that of carrageenan is 200,000 to 800,000. Concern has been raised about the amount of material in carrageenan with molecular weight less than 50,000. The actual amount (well under 1 percent) cannot even be detected accurately with current technology. Certainly it presents no threat to human health.  

Q: What is the importance of these molecular weight differences?

A: Poligeenan contains a fraction of material low enough in molecular weight that it can penetrate the walls of the digestive tract and enter the blood stream. The molecular weight of carrageenan is high enough that this penetration is impossible. Animal feeding studies starting in the 1960s have demonstrated that once the low molecular weight fraction of poligeenan enters the blood stream in large enough amounts, pre-cancerous lesions begin to form. These lesions are not observed in animals fed with a food containing carrageenan.

Q: Does carrageenan get absorbed in the digestive track?

A: Carrageenan passes through the digestive system intact, much like food fiber. In fact, carrageenan is a combination of soluble and insoluble nutritional fiber, though its use level in foods is so low as not to be a significant source of fiber in the diet.

Additional information

On June 11, 2008, Dr. Joanne Tobacman petitioned the FDA to revoke the current regulations permitting use of carrageenan as a food additive. On June 11, 2012 the FDA denied her petition, categorically addressing and ultimately dismissing all of her claims; their rebuttal supported by the results of several in-depth, scientific studies. If you would like to read the full petition and FDA response, they can be accessed at http://www.regulations.gov/#!searchResults;rpp=25;po=0;s=FDA-2008-P-0347

 

Copyright © 1999 Vita-Myr International Inc All rights reserved.
Revised: 05/27/16

 

Statements on this page have not been evaluated by the Food and Drug Administration.These products are not intended to diagnose, treat, cure or prevent disease.